In a small Brazilian town, there resides an extraordinary duo of identical twins named Elis and Eloá. Their story serves as a beacon of resilience and the remarkable power of the human spirit. Afflicted with Hutchinson-Gilford Progeria Syndrome, a rare and fatal genetic disorder causing accelerated aging, these twins confront their adversities with remarkable grace and strength, earning admiration from people worldwide.
Understanding Hutchinson-Gilford Progeria syndrome
HGPS stands as an exceptionally rare disorder, impacting roughly 1 in 20 million newborns globally. Marked by rapid aging from early childhood, individuals with progeria often display growth delays, diminished body fat and hair, prematurely aged skin, joint stiffness, and severe cardiovascular issues. Typically, those with HGPS have an average life expectancy of about 14.5 years, though some may extend into their late teens or early twenties. This syndrome gained public attention through the film The Curious Case of Benjamin Button.
The condition is caused by a mutation in the LMNA gene, which produces the lamin A protein responsible for maintaining the structural integrity of the cell nucleus. The mutation results in the production of an abnormal version of the protein, called progerin, which causes cells to become unstable and die prematurely.
Elis and Eloá’s journey
Elis and Eloá swiftly captured attention because of their distinctive medical condition. Despite the physical hurdles imposed by progeria, their contagious smiles and steadfast optimism have emerged as beacons of hope and inspiration. Guilherme and Elismar, the twins’ parents, have dedicated their lives to offering the utmost care for their daughters, striving to ensure they experience as normal a life as feasible within the confines of their condition.
The family’s path has been far from easy. Their daily life is filled with demanding medical routines, including physiotherapy, aimed at addressing joint stiffness and preserving mobility. Despite these challenges, Elis and Eloá approach each day with remarkable bravery and an unparalleled enthusiasm for life, which is truly remarkable.
A global community of support
Elis and Eloá’s narrative has touched hearts worldwide, sparking a surge of solidarity from individuals and groups committed to promoting awareness about progeria and backing research endeavors. The Progeria Research Foundation, a pivotal entity in this realm, has played a vital role in propelling research forward and furnishing assistance to families grappling with the condition.
Through social media platforms, the twins’ journey is shared with a broad audience, fostering a sense of community and solidarity. Their family’s updates, documenting both the highs and lows of their daily lives, provide invaluable insights into the realities of living with progeria, while also spreading a message of hope and perseverance.
Advances in research and hope for the future
In recent years, there have been remarkable advancements in comprehending and addressing progeria. A notable milestone occurred in 2020 when the U.S. Food and Drug Administration (FDA) granted approval for the first progeria treatment: lonafarnib. This medication has demonstrated efficacy in prolonging the lives of children with progeria by mitigating the accumulation of progerin in cells, thereby decelerating the disease’s advancement.
Though a cure remains elusive, ongoing research presents promising prospects. Scientists are delving into gene-editing methodologies, like CRISPR, as potential means to rectify the genetic mutation at its root. For families such as Elis and Eloá’s, these breakthroughs offer a ray of hope for the future.
And in our other article, we recounted the remarkable story of a girl born without a nose, affectionately dubbed “Voldemort,” who refuses to let her differences define her.
My Sister Stole My Fiancé a Month Before the Wedding and My Parents Took Her Side — I Paid a Visit to Their Wedding
What was supposed to be the happiest day of my life turned into one that I’ll never forget. I went from being the bride-to-be to the uninvited wedding guest who crashed the event because she wanted revenge. But karma arrived at the venue before I could.
He made me feel like the luckiest woman in the world.
When I met Ethan two years ago, I was convinced I had found my forever. He was charming, witty, and knew exactly what to say to make me feel special! Seven months ago, when he proposed, I felt like the happiest woman alive—but I didn’t know I’d never become his wife.
A man proposing | Source: Midjourney
Another thing I came to love about Ethan was how hands-on he was. We planned our wedding together, down to every last detail! From the elegant banquet hall venue with a garden; to the cascading white roses and other flowers.
We also went to cake tastings to find the perfect one and even chose the song we’d dance to as husband and wife! Every moment felt perfect, like a fairytale—until it all came crashing down a month before the wedding.
A happy couple | Source: Midjourney
It happened on an ordinary Wednesday. I had left work early to surprise Ethan with his favorite takeout. It was something small, just a gesture to show how much I appreciated him.
I let myself into his apartment, already picturing the delighted look on his face when he saw me standing there with a bag full of burgers and fries.
But the moment I stepped inside, I knew something was wrong.
A suspicious woman arrives with takeout | Source: Midjourney
A woman’s coat was draped over the back of a chair. At first, I thought maybe he had a guest—a relative or a coworker. But when I heard soft laughter coming from the bedroom, my stomach twisted into a knot.
I approached the door, every step heavier than the last. My hands trembled as I reached for the doorknob and slowly pushed it open.
There, tangled in the sheets, was Ethan. With my older sister, Lauren!
A couple in bed | Source: Pexels
Time stopped as my mind struggled to process what I was seeing. My sister—my own flesh and blood—was in bed with the man I was supposed to marry in a month!
Lauren gasped and scrambled to cover herself, but Ethan? He just sat up, completely unbothered.
“Wait,” I choked out. “What the hell is this?”
My so-called groom sighed, running a hand through his hair like I was the one being unreasonable. “You weren’t supposed to find out like this.”
An unapologetic man | Source: Midjourney
“Find out what?!” I asked, my voice shaking. “That you’re a cheating liar?! That my own sister betrayed me?!”
Lauren’s face was pale, but she didn’t say a word. She just clutched the sheets to her chest, avoiding my gaze.
Ethan, however, dared to look me in the eye and say, “I love her.”
The words knocked the air out of my lungs. I wanted him to deny it, to say it was a mistake, but instead, he looked relieved—like a weight had been lifted off his shoulders. I couldn’t believe this was the same sweet man I had wanted to walk down the aisle with after he became my husband!
A shocked woman | Source: Midjourney
It was like he was two different people—the man I had gotten to know and this guy in bed with my sister.
“You love her?!” My voice cracked. “Then why the hell did you propose to me?!”
He exhaled like he was explaining something painfully obvious. “I thought I loved you. But things changed. Lauren and I… we’ve been seeing each other for a while.”
For a while…
My stomach turned. This wasn’t just a one-time thing. They had been sneaking around behind my back for who knows how long!
An angry and hurt woman | Source: Midjourney
I turned to Lauren. “How could you do this to me?!”
She finally spoke, her voice barely above a whisper. “I didn’t mean for it to happen, sis.”
I let out a hollow laugh. “Didn’t mean for it to happen?! You didn’t trip and fall into his bed, Lauren!”
Ethan stood up, wrapping an arm around her. “Look, I get that you’re hurt, but we didn’t want to keep lying to you.”
My hands clenched into fists. “Oh, you didn’t want to keep lying? That’s rich!”
I stormed out, shaking with rage and heartbreak. I thought that was the worst of it. I was wrong.
A heartbroken woman leaving | Source: Midjourney
A few days later, my parents called me over to talk. I had been bawling my eyes out since I made the discovery. My friends and bridesmaids came to comfort me, but I hadn’t heard from my parents until then.
I foolishly believed they would be on my side for a change. Instead, I walked into an ambush.
“We understand you’re upset,” my mom said, her tone patronizing.
“But Ethan and Lauren are in love,” my dad added. “You wouldn’t want to stand in the way of true love, would you?”
A man talking | Source: Midjourney
I stared at them in disbelief. “True love? Are you serious?!”
Mom sighed. “Sweetheart, you’ve always been independent. You’ll move on. But Lauren… she needs stability. And Ethan makes her happy.”
I felt like I was drowning. “So, what? Are you just replacing me with her?! Pretending like none of this even happened?!”
“We’re not taking sides,” my dad said, though his tone made it clear they already had.
Then, the final blow.
“They’re still having the wedding,” my mom said. “And, well, Lauren will be the bride.”
A woman talking | Source: Midjourney
I blinked. “You can’t be serious.”
“It’s already paid for,” she said as if that made any of this acceptable. “It would be a shame to let all those plans go to waste.”
I stood up so fast the chair screeched against the floor. “Unbelievable.”
“We’d like you to be happy for them,” Dad said.
I laughed bitterly. “You actually expect me to celebrate this?!”
An upset woman laughing | Source: Midjourney
Lauren had taken my fiancé, and my parents had taken her side—like they always did. They had always treated her better, and now they wanted me to smile as they supported her relationship with my fiancé?!
I walked out of that house and didn’t look back.
An upset woman leaving | Source: Midjourney
When the wedding came, I obviously wasn’t invited. That didn’t mean I wasn’t going to be there. I decided not to cause a scene. I wasn’t going to scream or throw cake. I just wanted to sneak in and wait until the officiant asked for objections.
Then, I’d get up and tell their guests and our mutual friends that the man Lauren was marrying had been my fiancé first! I planned to embarrass them and make their “special day” the worst one ever!
But when I arrived at the banquet hall, things were… off.
A woman arrives at a wedding | Source: Midjourney
There was no music. No laughter. Just silence, thick with tension. Guests stood frozen in place, and at the front of the room, uniformed officers swarmed.
“What’s going on?” I asked the nearest cop.
Before he could answer, I spotted my sister—still in her wedding dress, tears streaming down her face. My parents sat at a table, looking utterly shell-shocked.
But Ethan was nowhere to be seen.
A bride crying | Source: Midjourney
The cop turned to me. “Are you a guest?”
I hesitated before nodding. “Sort of. I was supposed to be the bride today.”
He sighed. “We came here to arrest the groom, but he wasn’t here. He was caught at the city bus station trying to leave town.”
I blinked. “What?!”
The officer gestured toward a group of detectives speaking to guests. “Turns out, he’s been running a long con. He’s a scam artist. He never planned on marrying anyone.”
I felt my heart race. “What did he do?”
A shocked woman talking to a cop | Source: Midjourney
The cop’s expression darkened. “He’s done this before—to three other women in the city. He took off with all the wedding gifts, the deposits, decorations, and whatever money he could get his hands on. He’s currently on the run.”
“He even lied about having family coming from Europe. He has no family. No guests. Nothing,” the policeman informed me.
Shock rippled through me. My parents were still frozen in disbelief. Lauren—the woman who had betrayed me—was now abandoned at the altar, sobbing while her last-minute bridesmaids comforted her.
A bride being comforted | Source: Midjourney
And for the first time in weeks, I smiled as I stood there, taking in the chaos before me.
Justice had been served!
As the guests started leaving, one of the officers approached me. “Hi, I saw you arrive. I hear Officer James say you dodged a bullet.”
I let out a breath I hadn’t realized I was holding. “Yeah. Guess I did.”
He gave me a small smile. “Would you like to grab a coffee sometime? You know, with someone who isn’t a criminal?”
I glanced at his name tag—Officer Matt.
A policeman | Source: Midjourney
For the first time in a while, I felt something other than anger and betrayal. Maybe a fresh start wasn’t such a bad idea.
That was a year ago.
And tomorrow? I’m marrying him!
Life has a funny way of working out.
A happy woman | Source: Midjourney
Sadly, Ethan’s first bride wasn’t the only woman ditched on her wedding day. In this story, the bride’s groom fails to arrive on time and instead, she discovers he’s been cheating. The heartbroken woman stands up tall and makes the most of the day.
This work is inspired by real events and people, but it has been fictionalized for creative purposes. Names, characters, and details have been changed to protect privacy and enhance the narrative. Any resemblance to actual persons, living or dead, or actual events is purely coincidental and not intended by the author.
The author and publisher make no claims to the accuracy of events or the portrayal of characters and are not liable for any misinterpretation. This story is provided “as is,” and any opinions expressed are those of the characters and do not reflect the views of the author or publisher.
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